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Preheat your oven to 350° F and grease a medium size baking dish (I used a 7x9 dish).
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In a large pan or pot, cook and drain the pasta according the package directions.
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Place the drained pasta back into the pot and mix with the marinara sauce, chicken, HALF of the mozzarella, HALF of the parmesan, and 1-2 tsp of Italian seasoning.
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Allow the mixture to simmer for a few minutes over medium-low heat and then spread it evenly onto the bottom of your baking dish; sprinkle the remaining mozzarella and parmesan cheese over top.
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In a small bowl, mix together the panko bread crumbs, melted butter and garlic powder; sprinkle it evenly over the top of the casserole.
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Bake uncovered on the center rack for about 15 minutes or until the panko crust turns golden brown.
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Serve alone or with salad, veggies and/or breadsticks. Enjoy!